The symptoms of AIDS are primarily the result of conditions that do not normally develop in individuals with healthy immune systems. Most of these conditions are infections caused by bacteria, viruses, fungi and parasites that are controlled by the elements of the immune system. Also, people with AIDS often have systemic symptoms of infection like fevers, sweats, swollen glands, chills, weakness and weight loss.
Pulmonary infections
Pneumocystis pneumonia is rare in healthy, immunocompetent people, but common among HIV-infected individuals. Tuberculosis (TB) is unique among infections associated with HIV. Is not easily treatable once identified.
Symptoms are usually constitutional and are not localized to one particular site, often affecting bone marrow, bone, urinary and gastrointestinal tracts, liver, regional lymph nodes, and the central nervous system.
Gastrointestinal infections
Esophagitis is an inflammation of the lining of the lower end of the esophagus. In HIV infected individuals, this is normally due to fungal or viral infections. Unexplained chronic diarrhea in HIV infection is due to many possible causes, in some cases, diarrhea may be a side effect of several drugs used to treat HIV, or it may simply accompany HIV infection.
Neurological and psychiatric involvement
Neurological and psychiatric involvement HIV infection may lead to a variety of neuropsychiatric sequelae, either by infection of nervous system by organisms, or as a direct consequence of the illness. it usually infects the brain, it can cause fevers, headache, fatigue, nausea, and vomiting.
Tumors and malignancies
Tumors and malignancies patients with HIV infection have increased incidence of several cancers. This is primarily due to co-infection with an oncogenic DNA virus. Kaposi's sarcoma (KS) is the most common tumor in HIV-infected patients. Invasive cervical cancer in HIV-infected women is also considered AIDS-defining. It is caused by human papillomavirus (HPV). In addition to the AIDS-defining tumors listed above, HIV-infected patients are at increased risk of certain other tumors.
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